Long story short, your best chance for success when picking a tackle is round 1 from a power 5 school with a lot of starts.
As you might expect, tackle ranks second only to quarterback in the median pick of its star players and its first-round percentage. Of the 27 Pro Bowl/All-Pro tackles, 14 were drafted within the first 15 overall picks. Dismiss the value of a backup swing tackle at your own peril, but if you want to swing for upside, it’s basically first round or bust. There have actually been more undrafted Pro Bowl tackles (three) than Pro Bowl tackles drafted in Rounds 4 through 7 (two, at least until Jordan Mailata makes it).